Protein Purification Scientist
- Research & Development
- Denmark - Måløv
Do you want to work with method development for purification of new proteins in our biopharm portfolio? We offer you a dynamic job in close interaction with talented and dedicated colleagues. Your contribution will be significant for progress in our research pipeline.
About the department
The department of Protein Purification Technology is part of Biotechnology area, in Biopharmaceutical Research Unit, and is responsible for protein purification, in-process analysis and early stage process development covering lab and mini-pilot scale. We are currently 9 scientists and 12 laboratory technicians, who are engaged in research activities directed towards discovery and development of protein therapeutics for improved treatment of haemophilia, inflammation and growth hormone related disorders.
The job
You will represent the department in research project group, where you will be responsible for protein purification, in-process analysis and downstream process development. Your job tasks are to develop methods and perform purifications in order to deliver the protein for in vitro and in vivo studies in early research phases. The proteins in our pipeline are very diverse and include coagulation factors, antibodies and their fragments, or are chemically modified. Optionally, you can give input to protein design and contribute to selection of the lead candidate. The job also includes downstream process development for toxicological studies and early clinical trials in collaboration with our colleagues in CMC development. Furthermore, one of your main job tasks is to develop and perform in-process analyses to support process development and to ensure high protein quality. The scale of purifications varies between few micrograms to grams of the protein, where you can optionally use an Äkta Pilot. It is your responsibility to ensure that protein purification is performed in a manner that is adequate for the final use of the purified material.
Qualifications
You hold a PhD in chemical engineering, biotechnology, biochemistry or related disciplines. You have solid knowledge of process development from either an academic unit or biopharmaceutical industry. The ideal candidate has worked with a diversity of separation methods and has a profound understanding of the mechanisms and interactions involved in various kinds of chromatography. You have experience with using Äkta systems and can work independently. A fundamental knowledge of protein chemistry and protein stability is required. As a person you can stay focused in a sometimes busy working day and you always approach tasks and colleagues with a positive attitude and energy.
At Novo Nordisk, we strive for excellence. As a world leader in diabetes care and a major player in haemostasis management, growth hormone therapy and hormone replacement therapy, we offer our employees opportunities for continuous development.
Contact
For further information, please contact Head of Dept. Haleh Ahmadian at +45 3079 1221.
Deadline
30 August 2013.
- Research & Development
- Denmark - Måløv
Do you want to work with method development for purification of new proteins in our biopharm portfolio? We offer you a dynamic job in close interaction with talented and dedicated colleagues. Your contribution will be significant for progress in our research pipeline.
About the department
The department of Protein Purification Technology is part of Biotechnology area, in Biopharmaceutical Research Unit, and is responsible for protein purification, in-process analysis and early stage process development covering lab and mini-pilot scale. We are currently 9 scientists and 12 laboratory technicians, who are engaged in research activities directed towards discovery and development of protein therapeutics for improved treatment of haemophilia, inflammation and growth hormone related disorders.
The job
You will represent the department in research project group, where you will be responsible for protein purification, in-process analysis and downstream process development. Your job tasks are to develop methods and perform purifications in order to deliver the protein for in vitro and in vivo studies in early research phases. The proteins in our pipeline are very diverse and include coagulation factors, antibodies and their fragments, or are chemically modified. Optionally, you can give input to protein design and contribute to selection of the lead candidate. The job also includes downstream process development for toxicological studies and early clinical trials in collaboration with our colleagues in CMC development. Furthermore, one of your main job tasks is to develop and perform in-process analyses to support process development and to ensure high protein quality. The scale of purifications varies between few micrograms to grams of the protein, where you can optionally use an Äkta Pilot. It is your responsibility to ensure that protein purification is performed in a manner that is adequate for the final use of the purified material.
Qualifications
You hold a PhD in chemical engineering, biotechnology, biochemistry or related disciplines. You have solid knowledge of process development from either an academic unit or biopharmaceutical industry. The ideal candidate has worked with a diversity of separation methods and has a profound understanding of the mechanisms and interactions involved in various kinds of chromatography. You have experience with using Äkta systems and can work independently. A fundamental knowledge of protein chemistry and protein stability is required. As a person you can stay focused in a sometimes busy working day and you always approach tasks and colleagues with a positive attitude and energy.
At Novo Nordisk, we strive for excellence. As a world leader in diabetes care and a major player in haemostasis management, growth hormone therapy and hormone replacement therapy, we offer our employees opportunities for continuous development.
Contact
For further information, please contact Head of Dept. Haleh Ahmadian at +45 3079 1221.
Deadline
30 August 2013.